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Image Search Results
Journal: Cancer Research Communications
Article Title: HER2-selective and reversible tyrosine kinase inhibitor tucatinib potentiates the activity of T-DM1 in preclinical models of HER2-positive breast cancer
doi: 10.1158/2767-9764.crc-23-0302
Figure Lengend Snippet: FIGURE 6 The combined suppression of HER2 signaling by tucatinib and T-DM1 is associated with reduced tumor growth. A, ELISAs quantifying phosphorylation of signaling components downstream of HER2 in BT-474 cells (as percentage phosphorylated protein vs. untreated cells with SEMs). B, IHC images of pHER2, pHER3, pAKT, and pMEK staining of the BT-474 xenograft tumor model. Inlay images represent HER2-stained tumor
Article Snippet:
Techniques: Phospho-proteomics, Staining